Research Assistants

Publications

42.

The Biosynthetic Gene Cluster of Mushroom-Derived Antrocin Encodes Two Dual Functional Haloacid Dehalogenase-Like Terpene Cyclases

Angew. Chem. Int. Ed. 2022. e202215566.(10.1002/anie.202215566)

Tzu-Ho Chen, Chien-Ting Chen, Chi-Fang Lee, Rou-Jie Huang, Kuan-Lin Chen, Yuan-Chun Lu, Suh-Yuen Liang, Mai-Truc Pham, Yerra Koteswara Rao, Shih-Hsiung Wu, Rong-Jie Chein, Hsiao-Ching Lin*

41.

(Thiolan-2-yl)diphenylmethanol Benzyl Ether-Catalyzed Asymmetric Cyclopropanation of Chalcones

J. Org. Chem. 2022. Articles ASAP. (10.1021/acs.joc.2c02573)

Yu-Chen Gun, Kuei-Wei Chiu, and Rong-Jie Chein*

40.

Oxathiaborolium-catalyzed enantioselective [2 + 2] cycloadditions

Org. Biomol. Chem., 2022, 20, 8405-8409. (10.1039/d2ob01779b)

Soumendranath Mukhopadhyay, Ramalingam Boobalan and Rong-Jie Chein*

39.

Total Synthesis of (–)-Panduratin D

Chem. Commun., 2022, 58, 8564-8567. (10.1039/D2CC02980D)

Suhas Ravindra Bavikar, Hong-Jay Lo, Chebolu Naga Sesha Sai Pavan Kumar and Rong-Jie Chein*

38.

[B–Cl–B]+ Cations：Chloroborane Masked Chiral Borenium Ions

Inorg. Chem. 2021, 61, 16266-16272. (10.1021/acs.inorgchem.1c02073)

Ding-Nan Shih, Ramalingam Boobalan, Yi-Hung Liu, Rong-Jie Chein*, Ching-Wen Chiu*

37.

Organoselenium-Catalyzed Asymmetric
Cyclopropanations of (E)-Chalcones

Org. Lett. 2021, 23, 8104-8108. (10.1021/acs.orglett.1c03243)

Pei-Tung Cheng, Yu-Hsun Tseng and Rong-Jie Chein*

36.

Oxathiaborolium-Catalyzed Enantioselective [4 + 2] Cycloaddition and Its Application in Lewis Acid Coordinated and Chiral Lewis Acid Catalyzed [4 + 2] Cycloaddition

Org. Lett. 2021, 23, 6760-6764. (10.1021/acs.orglett.1c02345)

Ramalingam Boobalan and Rong-Jie Chein*

35.

Chiral Tetra-Coordinate Aluminum Cation in Catalysis

Organometallics. 2021, 40, 1244-1251. (10.1021/acs.organomet.1c00036)

Ching-Pei Hsu, Yi-Hung Liu, Ramalingam Boobalan, Ya-Fan Lin, Rong-Jie Chein*, and Ching-Wen Chiu*

34.

An Enzyme-Mediated Aza-Michael Addition Is Involved in the Biosynthesis of an Imidazoyl Hybrid Product of Conidiogenone B

Org. Lett. 2021, 23, 1904-1909. (10.1021/acs.orglett.1c00330)

Ranuka T. Hewage, Rou-Jie Huang, Shu-Jung Lai, Ya-Chu Lien, Shao-Hsing Weng, Dehai Li, Yu-Ju Chen, Shih-Hsiung Wu, Rong-Jie Chein*, and Hsiao-Ching Lin*

33.

Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection

PNAS 2021, 118, e2021579118. (10.1073/pnas.2021579118)

Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Yu-Pu Juang, Hsiu-Hua Ma, Ying-Ta Wu, Wen-Bin Yang, Cheng-Wei Cheng, Xiaorui Chen, Ting-Hung Chou, Jiun-Jie Shie, Wei-Chieh Cheng, Rong-Jie Chein, Shi-Shan Mao, Pi-Hui Liang*, Che Ma*, Shang-Cheng Hung*, and Chi-Huey Wong*

32.

Total Synthesis and Absolute Structure of N55, a Positive Modulator of GLP-1 Signaling

Org. Biomol. Chem. 2020, 18, 8899-8907. (10.1039/D0OB01722A)

Nai-Pin Lin and Rong-Jie Chein*

31.

Discovery of a Dual Function Cytochrome P450 that Catalyzes Enyne Formation in Cyclohexanoid Terpenoid Biosynthesis

Angew. Chem. Int. Ed. 2020, 59, 13537-13541. (10.1002/anie.202004435)

Yu-Rong Chen, Annavareddi Naresh, Suhas-Yuen Liang, Chun-Hung Ling, Rong-Jie Chein*, and Hsiao-Ching Lin*

30.

Enzyme-Catalyzed Azepinoindole Formation in Clavine Alkaloid Biosynthesis

Org. Lett. 2020, 22, 3302-3306.(10.1021/acs.orglett.0c01132)

Kuan-Lin Chen, Chen-Yu Lai, Mau-Truc Pham, Rong-Jie Chein, Yi Tang, and Hsiao-Ching Lin*

29.

Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein

J. Med. Chem. 2020, 63, 3172-3187. (10.1021/acs.jmedchem.9b01783)

Chia-Yi Lin, Hsin-Yi Wu, Ting-Jen Rachel Cheng, Jyung-Hurng Liu, Rou-Jie Huang, Tzu-Hung Hsiao, Chia-Jen Wang, Pei-Fang Hung, Albert Lan, Szu-Hua Pan*, Rong-Jie Chein*, Chi-Huey Wong and Pan-Chyr Yang

28.

ZnI2/Zn(OTf)2–TsOH: A Versatile Combined-Acid System for Catalytic Intramolecular Hydrofunctionalization and Polyene Cyclization

Chem. Commun. 2019, 55, 13522-13525. (10.1039/C9CC07242J)

Ting-Hung Chou, Bo-Hung Yu, Rong-Jie Chein*

27.

4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting thecolchicine site of β-tubulin

Eur. J. Med. Chem. 2019, 181, 111584. (10.1016/j.ejmech.2019.111584)

Ming-Shiu Lin, Tse-Ming Hong, Ting-Hung Chou, Shuenn-Chen Yang, Wei-Chia Chung, Chia-Wei Weng, Mei-Ling Tsai, Ting-Jen Rachel Cheng, Jeremy J W Chen, Te-Chang Lee, Chi-Huey Wong, Rong-Jie Chein*, Pan-Chyr Yang*

26.

From Carbamate to Chalcone: Consecutive Anionic Fries Rearrangement, Anionic Si→C Alkyl Rearrangement and Claisen-Schmidt Condensation

Org. Lett. 2018, 20(17), pp5362-5366. (10.1021/acs.orglett.8b02269). Highlighted by Synfacts 2018, 14(11), 1180. (10.1055/s-0037-1611034) 

Singam Naveen Kumar, Suhas Ravindra Bavikar, Chebolu Naga Sesha Sai Pavan Kumar, Isaac Furay Yu, Rong-Jie Chein*

25.

2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction

Cancer Sci. 2018, 109(3), 832-842. (10.1111/cas.13489)

Hao-Wei Cheng, Rong-Jie Chein, Ting-Jen Cheng, Pei-Shan Wu, Hsin-Yi Wu, Pei-Fang Hung, Chia-Jen Wang, Yuan-Ling Hsu, Jau-Min Wong, Ang Yuan, Chi-Huey Wong, Pan-Chyr Yang, Szu-Hua Pan*

24.

Oxathiaborolium: a Type of Chiral Lewis Acid Catalyst and Its Application in Catalytic and Highly Enantioselective Diels−Alder Reactions

Org. Lett. 2017, 19(1), 22-25. (10.1021/acs.orglett.6b03147). Highlighted by C&EN 2017.

Singam Naveen Kumar, Isaac Furay Yu, Rong-Jie Chein*

23.

Total Synthesis of the Labdane Diterpenes Galanal A and Galanal B from Geraniol

J. Org. Chem. 2017, 82(3), 1575–1583. (10.1021/acs.joc.6b02766)

Shih-Che Lin, Rong-Jie Chein*

22.

(Thiolan-2-yl)diphenylmethyl Benzyl Ether/N,N’-diarylurea Cocatalyzed Asymmetric Aziridination of Cinnamyl Bromide and Aryl Aldimine

Tetrahedron 2016, 72, 2607-2615. (10.1016/j.tet.2014.12.063)

Shang-Hua Wang, and Rong-Jie Chein*

21.

Cytotoxicityof Postmodified Zeolitic-Imidazolate Framework-90 (ZIF-90) Nanocrystals: Correlation between Functionality and Toxicity

Chem. Eur. J. 2016, 22, 2925-2929. (10.1002/chem.201505005)

Chia-I Yen, Szu-Mam Liu, Wei-Shang Lo, Jhe-Wei Wu, Yi-Hsin Liu, Rong-Jie Chein, Renqiang Yang, Kevin C.-W. Wu, Jih Ru Hwu, Nianhan Ma,* Fa-Kuen Shieh*

20.

Isolation of Positive Modulator of Glucagon-like Peptide-1 Signaling from Trigonella foenum-graecum (Fenugreek) Seed

J. Biol. Chem. 2015, 290, 26235-26248. (10.1074/jbc.M115.672097)

Klim King*, Nai-Pin Lin, Yu-Hong Cheng, Gao-Hui Chen, Rong-Jie Chein*

19.

Cation ion specifically induces a conformational change in trans-dehydroandrosterone – A solid-state NMR study

Steroids 2015, 96, 73-80. (10.1016/j.steroids.2015.01.011)

Darong Wang, Meiman Chen, Rong-Jie Chein, Wei-Min Ching, Chen-Hsiung Hung, Der-Lii M. Tzou*

18.

Lithiation of a Silyl Ether: Anionic Si→C Alkyl Migration

Synlett 2014, 25, 2827–2830. (10.1055/s-0034-1379493)

Chin-Yin Lin, Rong-Jie Chein*

17.

Lithiation of a Silyl Ether; Formation on an ortho-Fries Hydroxyketone

Angew. Chem. Int. Ed. 2014, 53, 9026 –9029. (10.1002/anie.201404495)

Hong-Jay Lo, Chin-Yin Lin, Mei-Chun Tseng, and Rong-Jie Chein*

16.

Synthesis of Labdane Diterpenes Galanal A and B from (+)–Sclareolide

Org. Lett. 2014, 16, 2990−2992. (10.1021/ol501121v)

Chebolu Naga Sesha Sai Pavan Kumar, Rong-Jie Chein*

15.

Enantioselective Synthesis of Diaryl Aziridines Using Tetrahydrothiophene-Based Chiral Sulfides as Organocatalysts

Chem. Commun. 2014, 50, 1101-1103. (10.1039/C3CC47550F)

Meng-Ting Huang, Hsin-Yi Wu, Rong-Jie Chein*

14.

From Precursor to Catalyst: The Involvement of [Ru(ƞ5-Cp*)Cl2]2 in Highly Branch Selective Allylic Etherfication of Cinnamyl Chloride

Tetrahedron Lett. 2014, 55, 1031-1035. (10.1016/j.tetlet.2013.12.074)

Ravi Kumara Guralamatta Siddappa, Chih-Wei Chang, Rong-Jie Chein

13.

Enantioselective Synthesis of (Thiolan-2-yl)diphenylmethanol and Its Application in Asymmetric, Catalytic Sulfur Ylide-Mediated Epoxidation

J. Org. Chem. 2013, 78, 5788-5793. (10.1021/jo400648f)

Hsin-Yi Wu, Chih-Wei Chang, Rong-Jie Chein*

12.

The Absolute Configuration of Anti-HIV-1 Agent (-)-Concentricolide : Total Synthesis of (+)-(R)-Concentricolide

J. Org. Chem. 2011, 76, 4154-4157. (10.1021/jo2004132)

Chih-Wei Chang, Rong-Jie Chein*

11.

Strong Conformational Preferences of Heteroaromatic Ethers and Electron Pair Repulsion

Org. Lett. 2010, 12, 132-135. (10.1021/ol9025364)

Rong-Jie Chein, E. J. Corey*

10.

Highly Enantioselective Oxazaborolidine-Catalyzed Reduction of 1,3-Dicarbonyl Compounds: Role of the Additive Diethylaniline

Organic Letters 2009, 11, 1611-1614. (10.1021/ol900258f)

Rong-Jie Chein, Ying-Yeung Yeung and E. J. Corey*

09.

Conformational Energetics of Cationic Backbone Rearrangements in Triterpenoid Biosynthesis Provide an Insight into Enzymatic Control of Product

J. Am. Chem. Soc. 2008, 130, 9031-9036. (10.1021/ja800980h)

László Kürti, Rong-Jie Chein and E. J. Corey*

08.

Conversion of Torgov’s Synthesis of Estrone into a Highly Enantioselective and Efficient Process

J. Am. Chem. Soc. 2007, 129, 10346-10347. (10.1021/ja0742434)

Ying-Yeung Yeung, Rong-Jie Chein, and E. J. Corey*

07.

Ritter Reaction of 1-Aryl-1-fluoro-2-haloethanes

J. Chin. Chem. Soc. 2006, 53, 429-430. (10.1002/jccs.200600054)

Tse-Lok Ho, Rong-Jie Chein

06.

Total Synthesis of (+)-β-Himachalene

Helv. Chim. Acta. 2006, 89, 231-239. (10.1002/hlca.200690025)

Tse-Lok Ho, Rong-Jie Chein

05.

Unusual Thionation via Fragmentation

J. Chin. Chem. Soc. 2005, 52, 1223-1225. (10.1002/jccs.200500176)

Tse-Lok Ho, Rong-Jie Chein

04.

Intervention of Phenonium Ion in Ritter Reactions

J. Org. Chem. 2004, 69, 591-592. (10.1021/jo035561y)

Tse-Lok Ho, Rong-Jie Chein

03.

Total Synthesis of (±)-2-Isocyanoallopupukeanane

J. Org. Chem. 2000, 65, 5774-5779. (10.1021/jo000668w)

Tse-Lok Ho*, Liang-Ren Kung, and Rong-Jie Chein

02.

A Synthesis of 6-Myoporol

J. Nat. Prod. 1997, 60, 493-494. (10.1021/np960704f)

Tse-Lok Ho*, and Rong-Jie Chein

01.

Synthesis of (-)-Furodysinin from (+)-Limonene

Chem. Commun. 1996, 1147. (10.1039/CC9960001147)

Tse-Lok Ho, Rong-Jie Chein

The Chein Laboratory