Publications

  1. Nai-Pin Lin and Rong-Jie Chein* “Total Synthesis and Absolute Structure of N55, a Positive Modulator of GLP-1 Signaling” Org. Biomol. Chem. 2020, accepted. (10.1039/D0OB01722A)

  2. Yu-Rong Chen, Annavareddi Naresh, Suhas-Yuen Liang, Chun-Hung Ling, Rong-Jie Chein,* and Hsiao-Ching Lin* “Discovery of a Dual Function Cytochrome P450 that Catalyzes Enyne Formation in Cyclohexanoid Terpenoid Biosynthesis” Angew. Chem. Int. Ed. 2020, 59, 13537-13541. (10.1002/anie.202004435)

  3. Kuan-Lin Chen, Chen-Yu Lai, Mau-Truc Pham, Rong-Jie Chein, Yi Tang, and Hsiao-Ching Lin* “Enzyme-Catalyzed Azepinoindole Formation in Clavine Alkaloid Biosynthesis” Org. Lett. 2020, 22, 3302-3306. (10.1021/acs.orglett.0c01132)

  4. Chia-Yi Lin, Hsin-Yi Wu, Ting-Jen Rachel Cheng, Jyung-Hurng Liu, Rou-Jie Huang, Tzu-Hung Hsiao, Chia-Jen Wang, Pei-Fang Hung, Albert Lan, Szu-Hua Pan*, Rong-Jie Chein*, Chi-Huey Wong and Pan-Chyr Yang “Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein” J. Med. Chem. 202063, 3172-3187. (10.1021/acs.jmedchem.9b01783)

  5. Ting-Hung Chou, Bo-Hung Yu, Rong-Jie Chein* “ZnI2/Zn(OTf)2–TsOH: A Versatile Combined-Acid System for Catalytic Intramolecular Hydrofunctionalization and Polyene Cyclization” Chem. Commun. 2019, 55, 13522-13525. (10.1039/C9CC07242J)

  6. M.-S. Lin, T.-M. Hong, T.-H. Chou, S.-C. Yang, W.-C. Chung, C.-W. Weng,M.-L. Tsai, T.-J. Rachel Cheng, J.J.W. Chen, T.-C. Lee, C.-H. Wong, R.-J. Chein*, P.-C. Yang* “4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting thecolchicine site of β-tubulin” European Journal of Medicinal Chemistry 2019, 181, 111584. (10.1016/j.ejmech.2019.111584)

  7. Singam Naveen Kumar, Suhas Ravindra Bavikar, Chebolu Naga Sesha Sai Pavan Kumar, Isaac Furay Yu, Rong-Jie Chein* “From Carbamate to Chalcone: Consecutive Anionic Fries Rearrangement, Anionic Si→C Alkyl Rearrangement and Claisen-Schmidt Condensation” Org. Lett. 2018, 20(17), pp5362-5366. (10.1021/acs.orglett.8b02269) Highlighted by Synfacts 2018, 14(11), 1180. (10.1055/s-0037-1611034)

  8. Hao-Wei Cheng, Rong-Jie Chein, Ting-Jen Cheng, Pei-Shan Wu, Hsin-Yi Wu, Pei-Fang Hung, Chia-Jen Wang, Yuan-Ling Hsu, Jau-Min Wong, Ang Yuan, Chi-Huey Wong, Pan-Chyr Yang, Szu-Hua Pan* “2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction” Cancer Sci. 2018, 109(3), 832-842. (10.1111/cas.13489)

  9. Singam Naveen Kumar, Isaac Furay Yu, Rong-Jie Chein* “Oxathiaborolium: a Type of Chiral Lewis Acid Catalyst and Its Application in Catalytic and Highly Enantioselective Diels−Alder Reactions” Org. Lett. 201719(1), 22-25. (10.1021/acs.orglett.6b03147). Highlighted by C&EN 2017.

  10. Shih-Che Lin, Rong-Jie Chein* “Total Synthesis of the Labdane Diterpenes Galanal A and Galanal B from Geraniol”  J. Org. Chem. 201782(3), 1575–1583. (10.1021/acs.joc.6b02766)

  11. Shang-Hua Wang, and Rong-Jie Chein* “(Thiolan-2-yl)diphenylmethyl Benzyl Ether/N,N’-diarylurea Cocatalyzed Asymmetric Aziridination of Cinnamyl Bromide and Aryl Aldimine” TETRAHEDRON 2016, 72, 2607-2615. (10.1016/j.tet.2014.12.063)

  12. Chia-I Yen, Szu-Mam Liu, Wei-Shang Lo, Jhe-Wei Wu, Yi-Hsin Liu, Rong-Jie Chein, Renqiang Yang, Kevin C.-W. Wu, Jih Ru Hwu, Nianhan Ma,* Fa-Kuen Shieh* “Cytotoxicityof Postmodified Zeolitic-Imidazolate Framework-90 (ZIF-90) Nanocrystals: Correlation between Functionality and Toxicity” CHEMISTRY-A EUROPEAN JOURNAL 2016, 22, 2925-2929. (10.1002/chem.201505005)

  13. Klim King*, Nai-Pin Lin, Yu-Hong Cheng, Gao-Hui Chen, Rong-Jie Chein* “Isolation of Positive Modulator of Glucagon-like Peptide-1 Signaling from Trigonella foenum-graecum (Fenugreek) Seed” J. Biol. Chem. 2015290, 26235-26248. (10.1074/jbc.M115.672097)

  14. Darong Wang, Meiman Chen, Rong-Jie Chein, Wei-Min Ching, Chen-Hsiung Hung, Der-Lii M. Tzou* “Cation ion specifically induces a conformational change in trans-dehydroandrosterone – A solid-state NMR study” STEROIDS 2015, 96, 73-80. (10.1016/j.steroids.2015.01.011)

  15. Chin-Yin Lin, Rong-Jie Chein* “Lithiation of a Silyl Ether: Anionic Si→C Alkyl Migration” SYNLETT 2014, 25, 2827–2830. (10.1055/s-0034-1379493)

  16. Hong-Jay Lo, Chin-Yin Lin, Mei-Chun Tseng, and Rong-Jie Chein* “Lithiation of a Silyl Ether; Formation on an ortho-Fries Hydroxyketone” Angew. Chem. Int. Ed. 2014, 53, 9026 –9029. (10.1002/anie.201404495)

  17. Chebolu Naga Sesha Sai Pavan Kumar, Rong-Jie Chein* “Synthesis of Labdane Diterpenes Galanal A and B from (+)–Sclareolide” Org. Lett. 2014, 16, 2990−2992. (10.1021/ol501121v)

  18. Meng-Ting Huang, Hsin-Yi Wu, Rong-Jie Chein* “Enantioselective Synthesis of Diaryl Aziridines Using Tetrahydrothiophene-Based Chiral Sulfides as Organocatalysts” Chem. Commun. 2014, 50, 1101-1103. (10.1039/C3CC47550F)

  19. Ravi Kumara Guralamatta Siddappa, Chih-Wei Chang, Rong-Jie Chein “From Precursor to Catalyst: The Involvement of [Ru(ƞ5-Cp*)Cl2]2 in Highly Branch Selective Allylic Etherfication of Cinnamyl Chloride” TETRAHEDRON LETTERS 2014, 55, 1031-1035. (10.1016/j.tetlet.2013.12.074)

  20. Hsin-Yi Wu, Chih-Wei Chang, Rong-Jie Chein* “Enantioselective Synthesis of (Thiolan-2-yl)diphenylmethanol and Its Application in Asymmetric, Catalytic Sulfur Ylide-Mediated Epoxidation” J. Org. Chem. 2013, 78, 5788-5793. (10.1021/jo400648f)

  21. Chih-Wei Chang, Rong-Jie Chein* “The Absolute Configuration of Anti-HIV-1 Agent (-)-Concentricolide : Total Synthesis of (+)-(R)-Concentricolide” J. Org. Chem. 2011, 76, 4154-4157. (10.1021/jo2004132)

  22. Rong-Jie Chein, E. J. Corey* “Strong Conformational Preferences of Heteroaromatic Ethers and Electron Pair Repulsion” Org. Lett. 2010, 12, 132-135. (10.1021/ol9025364)

  23. Rong-Jie Chein, Ying-Yeung Yeung and E. J. Corey* “Highly Enantioselective Oxazaborolidine-Catalyzed Reduction of 1,3-Dicarbonyl Compounds: Role of the Additive Diethylaniline” Organic Letters 200911, 1611-1614. (10.1021/ol900258f)

  24. László Kürti, Rong-Jie Chein and E. J. Corey* “Conformational Energetics of Cationic Backbone Rearrangements in Triterpenoid Biosynthesis Provide an Insight into Enzymatic Control of Product” J. Am. Chem. Soc. 2008130, 9031-9036. (10.1021/ja800980h)

  25. Ying-Yeung Yeung, Rong-Jie Chein, and E. J. Corey* “Conversion of Torgov’s Synthesis of Estrone into a Highly Enantioselective and Efficient Process” J. Am. Chem. Soc. 2007129, 10346-10347. (10.1021/ja0742434)

  26. Tse-Lok Ho, Rong-Jie Chein “Ritter Reaction of 1-Aryl-1-fluoro-2-haloethanes” J. Chin. Chem. Soc. 200653, 429-430. (10.1002/jccs.200600054)

  27. Tse-Lok Ho, Rong-Jie Chein “Total Synthesis of (+)-β-Himachalene” Helv. Chim. Acta. 2006, 89, 231-239. (10.1002/hlca.200690025)

  28. Tse-Lok Ho, Rong-Jie Chein “Unusual Thionation via Fragmentation” J. Chin. Chem. Soc. 200552, 1223-1225. (10.1002/jccs.200500176)

  29. Tse-Lok Ho, Rong-Jie Chein “Intervention of Phenonium Ion in Ritter Reactions” J. Org. Chem. 200469, 591-592. (10.1021/jo035561y)

  30. Tse-Lok Ho*, Liang-Ren Kung, and Rong-Jie Chein “Total Synthesis of (±)-2-Isocyanoallopupukeanane” J. Org. Chem. 200065, 5774-5779. (10.1021/jo000668w)

  31. Tse-Lok Ho*, and Rong-Jie Chein “A Synthesis of 6-Myoporol” J. Nat. Prod. 199760, 493-494. (10.1021/np960704f)

  32. Tse-Lok Ho, Rong-Jie Chein “Synthesis of (-)-Furodysinin from (+)-Limonene” Chem. Commun. 1996, 1147. (10.1039/CC9960001147)

Patents:

  1. R.O.C. I516474「良薑化合物及其類似物之合成」

  2. US patent US 9,193,665 B2 “Synthesis of Galanal Compounds and Analogues thereof”